Orlistat

Orlistat is a weight loss medicine that prevents the action of enzymes found in the digestive juices which break down fats in our diet. As a result, about 30% of the fat that is eaten in the meals is not broken down and absorbed by the body. This means the body cannot use the fat as a source of energy or convert it into fat tissue. Instead, the fat is excreted in the faeces. Orlistat helps weight loss provided it is used in combination with a low-calorie diet and an exercise programme. Research has shown that Orlistat helps adults lose 50% more weight than by dieting alone.

Orlistat is used to aid weight loss in people who are overweight or clinically obese. Orlistat comes in two strengths. The 60-mg capsules are available without a prescription. The 120-mg capsules require a prescription and are prescribed to aid weight loss in obese people with a body mass index (BMI) of 28 kg/m² or more.

This medicine may cause side effects, including: Digestive problems (stomach ache, flatulence, fatty stools or diarrhoea); Headache; Low blood sugar levels; Flu or cold. In most cases these side effects will go away by themselves. You can avoid digestive problems by eating less fat. Please note that this medicine can cause diarrhoea, which if severe, can reduce the effectiveness of oral contraceptive pills. If you are taking the pill for contraception you may need to use an additional method of contraception to prevent pregnancy if you experience severe diarrhoea while taking this medicine. For more information on possible side effects, see the package leaflet.

Click here to view patient information leaflet