Get emergency medical help if you have any of these signs of an allergic reaction to Aldara: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Wash off the medicine and call your doctor at once if you have a serious skin reaction such as severe itching, burning, oozing, bleeding, or skin changes where the medicine is applied.
Stop using Aldara and call your doctor at once if you have a serious side effect such as flu symptoms such as fever, chills, body aches, tired feeling, swollen glands. When treating genital warts around the vagina, if you have severe swelling or urination problems, stop using Aldara and call your doctor right away.
Less serious Aldara side effects may include:
mild skin irritation, itching, dryness, flaking, scabbing, crusting, redness, or hardening of the skin where the medicine was applied;
changes in the color of treated skin;
headache, dizziness, chest pain, back pain;
cold sores, fever blisters;
cold symptoms such as stuffy nose, sneezing, sore throat;
nausea, diarrhea, loss of appetite; or
vaginal itching or discharge.